Craving a dish that combines the heartiness of beef, the silky melt of Velveeta, and a hint of Cajun spice? This creamy Velveeta penne pasta recipe is the perfect fusion of comfort and kick. The Cajun beef Alfredo sauce clings to every tube of pasta, delivering rich flavor in every bite.

Whether you’re feeding a hungry family or impressing guests with a one-skillet dinner, this recipe checks all the boxes. With just the right amount of heat and a creamy finish, it’s a dish that disappears fast and earns repeat requests.

Preparation Phase & Tools to Use

Before you dive into cooking, have your key tools ready. A large deep skillet or saute pan is crucial to sear the beef and simmer the Alfredo sauce without overcrowding. You’ll need a medium pot for boiling the penne pasta to al dente perfection. A colander is essential for draining the pasta, and a sturdy wooden spoon helps you break and stir the ground beef evenly.

Also, keep a cheese grater handy if you’re grating additional cheese toppings, and measuring cups/spoons for precise sauce seasoning. These tools streamline your workflow and help bring this recipe together with minimal mess.

Ingredients for the Creamy Velveeta Penne Pasta Recipe with Cajun Beef Alfredo Sauce

Penne Pasta – The sturdy tubes hold onto the thick, creamy sauce beautifully, making each bite satisfying.

Ground Beef – Provides savory depth and a hearty base for the Cajun Alfredo sauce.

Red Bell Pepper – Adds subtle sweetness and a pop of color to balance the spice.

Velveeta Cheese – This processed cheese ensures an ultra-creamy, silky texture in the sauce.

Heavy Cream – Gives the Alfredo sauce its rich, luxurious mouthfeel.

Cajun Seasoning – Brings bold heat and complexity; adjust to taste for spice level.

Garlic (minced) – Enhances the overall flavor with aromatic depth.

Shredded Mozzarella – Optional for broiling a bubbly cheese topping.

Fresh Parsley – For garnish and a fresh finish.

How To Make the Creamy Velveeta Penne Pasta Recipe with Cajun Beef Alfredo Sauce

Step 1: Cook the Pasta

Bring salted water to a boil in a medium pot. Add penne and cook until al dente according to package instructions. Drain and set aside.

Step 2: Sear the Beef

In a large skillet, brown the ground beef over medium-high heat. Use a wooden spoon to break it apart evenly. Drain excess fat if needed.

Step 3: Build the Flavor Base

Add minced garlic and diced red bell pepper to the skillet with the beef. Sauté for 3-4 minutes until softened and aromatic.

Step 4: Create the Cajun Alfredo Sauce

Pour in the heavy cream and stir in cubed Velveeta. Stir gently until the cheese is melted and sauce is smooth. Add Cajun seasoning to taste.

Step 5: Combine Pasta and Sauce

Add the cooked penne to the skillet. Toss gently to coat all pasta in the sauce. Let simmer for 2-3 minutes to marry the flavors.

Step 6: Optional Cheese Finish

Sprinkle shredded mozzarella on top and broil for 2-3 minutes until bubbly and golden. Garnish with chopped parsley.

Serving and Storing Creamy Velveeta Penne Pasta

Serve this rich, cheesy pasta hot, straight from the skillet to your plate. Pair it with a light green salad or roasted vegetables to cut through the creaminess.

To store leftovers, transfer cooled pasta into an airtight container and refrigerate for up to 3 days. Reheat in the microwave or on the stove with a splash of cream or milk to revive the sauce’s consistency.

Frequently Asked Questions

Can I use a different type of pasta?

Absolutely! Rotini, rigatoni, or fusilli also work well. Just aim for pasta that holds onto creamy sauces.

Is Velveeta necessary, or can I substitute?

Velveeta delivers unmatched creaminess, but you can use cream cheese or a combo of cheddar and mozzarella if preferred.

How spicy is the Cajun seasoning?

Most Cajun blends have a medium kick. Taste as you go—start with 1 teaspoon and adjust for your heat preference.

Can I make this dish ahead of time?

Yes, you can prepare the pasta and sauce separately, then combine and reheat before serving.

What protein can I substitute for ground beef?

Ground turkey, sausage, or even shrimp are great options to suit your taste or dietary needs.

Is this freezer-friendly?

Freezing is not ideal due to the dairy content, which may separate upon thawing. For best results, enjoy fresh or refrigerated.

Want More Creamy Pasta Ideas?

If you enjoy the spicy-creamy twist in this recipe, you’ll love these other hearty and cheesy pasta options:

Try the Delicious Beef Bowtie Pasta for another rich and beefy dinner that comes together fast. Or go for a spicier, robust profile with the Spicy Rattlesnake Pasta that’s equally creamy and bold.

For a playful bake, the Buffalo Chicken Lasagna layers heat and cream in a unique format. You might also explore the Beef and Bowtie Pasta with Alfredo Sauce for a smooth, indulgent combination.

Still hungry? Check out my Pinterest LadyPlate for daily creamy comfort recipes that bring joy to your weeknight meals.

Creamy Velveeta Penne Pasta Recipe with Cajun Beef Alfredo Sauce

Author: Julia Koch
Total Time: 30 minutes
Yield: 4 servings

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Description

This Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce is a bold, comforting meal that comes together in one skillet. Rich, cheesy, and loaded with flavor, it’s a go-to recipe for busy weeknights or impressing dinner guests. The creamy Velveeta blends perfectly with heavy cream and Cajun spice, coating the pasta and beef in irresistible goodness.